skip to Main Content

Landmark Research Series

Comparison of carvedilol and metoprolol on clinical outcomes in patients with CHF (COMET)

Clinical Question: What is the effect of carvedilol vs metoprolol tartrate on mortality and morbidity in patients with heart failure with reduced ejection fraction (HFrEF) and NYHA class II-IV symptoms?

Take Away: In patients with HFrEF, carvedilol reduces all-cause mortality compared to metoprolol tartrate.

 

 

Intensive versus Conventional Glucose Control in Critically Ill Patients (NICE-SUGAR)

This classic, often-cited article informs us that among patients in the ICU, intensive glucose control of 81-108 increased mortality as compared to a more liberal glucose target of <180.  How have you applied the findings of this research to your practice?

Rosuvastatin to Prevent Vascular Events (JUPITER)

Back To Top
Login
Log in below to access learning modules.
Forgot Password
Enter your email address or username and we’ll send you instructions to reset your password.