Comparison of carvedilol and metoprolol on clinical outcomes in patients with CHF (COMET)
EBM, Landmark Research
Clinical Question: What is the effect of carvedilol vs metoprolol tartrate on mortality and morbidity in patients with heart failure with reduced ejection fraction (HFrEF) and NYHA class II-IV symptoms? Take Away: In patients with HFrEF, carvedilol reduces all-cause mortality…