Thank you Dr. Brendan Cerk for an excellent presentation on neurocysticercosis presenting with new onset seizure

Teaching Points

• Histoplasmosis is a common endemic mycosis, usually asymptomatic but occasionally results in severe illness
• Hematogenous dissemination occurs during the acute infection before cellular immunity develops
• Diagnosis: serum and urine antigen
• Treatment: itraconazole for 12 months, if CNS then liposomal amphotericin B for 4-6 weeks then itrazonazole for an additional 12 months

Power Point: Morning Report 02-01-2017

Further Reading:
Histoplasmosis-Induced Hemophagocytic Lymphohistiocytosis in an Adult Patient A Case Report and Review of the Literature
Progressive disseminated histoplasmosis a systematic review on the performance of non-culture-based diagnostic tests