CURB-65: the easy-to-use clinical prediction rule helps us triage patients with pneumonia to inpatient or outpatient care. What is this actually based upon? This is the original study used to develop the CURB-65. Here are some things to think about…
This is the landmark trial that compares a restrictive to a liberal red blood cell transfusion strategy. Here are some things to think about when reading this article: What are our current pRBC transfusion goals for most patients? How are…
The General Medicine Wards (“GMED”) rotation at the VA West Los Angeles (VA-WLA) Medical Center is an inpatient clinical training experience that trains residents to competently care for patients with a broad range of medical problems within the Veterans Administration…
The Inpatient Medicine curriculum is a longitudinal, progressive educational program that reviews evidence-based medicine in the care of hospitalized patients. There is particular emphasis on research that impacts current practice guidelines ("landmark" trials). Residents are expected to engage in the…
Sepsis continues to affect 1.5 million people and lead to 250,000 deaths in the U.S., according to the CDC. The CORTICUS study reviewed here (article below) is the landmark study evaluating the potential benefit of corticosteroids in septic patients. As…
Influenza is still in season, and we are certainly seeing primary flu and secondary complications like pneumonia. So here’s an interesting question: does combination therapy with the addition of clarithromycin and naproxen in patients hospitalized for acute influenza have any benefit?
As general internists, we often encounter and are expected to medically manage the acute complications of decompensated cirrhosis: Gastrointestional bleed Spontaneous bacterial peritonitis Hepatic encephalopathy Hepatorenal syndrome This article tackles an important cornerstone of treatment for SBP: the use of…
Do you ever give NSAID’s to patients with cardiomyopathy? Usually not, and here is evidence supporting why we don’t. But are there some NSAID’s that have less unfavorable outcomes?