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Feb 20 2018

Combination Therapy in Influenza

EBM, Journal Club

Influenza is still in season, and we are certainly seeing primary flu and secondary complications like pneumonia.  So here’s an interesting question: does combination therapy with the addition of clarithromycin and naproxen in patients hospitalized for acute influenza have any benefit?

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Feb 01 2018

Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes

EBM, Landmark Research

Antagonists of the P2Y12 ADP receptor, in addition to aspirin, are the mainstay of treatment of non-ST elevation acute coronary syndromes (NSTE-ACS).  Although Clopidogrel (Plavix®) has been widely used for years, newer agents have come into use, including Ticagrelor (Brilinta®) and Prasugrel…

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Feb 01 2018

Effect of IV Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and SBP

EBM, Landmark Research

As general internists, we often encounter and are expected to medically manage the acute complications of decompensated cirrhosis: Gastrointestional bleed Spontaneous bacterial peritonitis Hepatic encephalopathy Hepatorenal syndrome This article tackles an important cornerstone of treatment for SBP: the use of…

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