What’s your differential diagnosis to explain the “strange behavior” of a patient with newly diagnosed HIV/AIDS?
Thank you Shirley for a great presentation on a young patient presenting with jaundice, AST 2552 and ALT >5000!
What’s the differential?
Thank you Dr. John Hollowed for an excellent presentation on acute promyelocytic leukemia
- APL accounts for 5-20% of AML cases
- Increased incidence in people with prior cytotoxic therapy
- Presents with complications of pancytopenia, weakness, fatigue, infections, increased bruising/bleeding, DIC
- Diagnosis: bone marrow analysis and confirmation with PCR, FISH, or cytogenic analysis
- Treatment is All-trans Retinoic Acid (ATRA)
Thank you Dr. Liza Buchbinder for an excellent presentation on Huntington’s Disease
- Etiology: Autosomal dominant; Drug induced (antipsychotics, estrogen containing); Endocrine (thyrotoxicosis, hyperglycemia); pregnancy (chorea gravidarum); streptococcal infection (Sydenham chorea); autoimmune (SLE, APLS); neurodegenerative d/o of basal ganglia.
- Associated w/ parkinsonism, impulsiveness, psychiatric disorders, and dementia.
- Treatment is symptomatic
Thank you Dr. Daniel Jimenez for an excellent presentation on TCA induced cardiotoxicity Teaching Points Clinical presentation: anticholinergic sx (urinary retention, constipation), CNS (seizures, coma), acidosis, arrythmias ECG: prolonged QRS/PR/QT --> predisposes for ventricular arrhythmias) Management: supportive care, benzos for seizures,…
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